Bianconi I, Jeukens J, Freschi L, Alcalá-Franco B, Facchini M, Boyle B, Molinaro A, Kukavica-Ibrulj I, Tümmler B, Levesque RC, Bragonzi A. Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection. BMC Genomics 2015; 16: 1105.
Fischer S, Klockgether J, Losada PM, Chouvarine P, Cramer N, Davenport CF, Dethlefsen S, Dorda M, Goesmann A, Hilker R, Mielke S, Schönfelder T, Suerbaum S, Türk O, Woltemate S, Wiehlmann L, Tümmler B. Intraclonal genome diversity of the major Pseudomonas aeruginosa clones C and PA14. Environ Microbiol Rep. 2015, Dec 28.
Freschi L, Jeukens J, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Laroche J, Larose S, Maaroufi H, Fothergill JL, Moore M, Winsor GL, Aaron SD, Barbeau J, Bell SC, Burns JL, Camara M, Cantin A, Charette SJ, Dewar K, Déziel É, Grimwood K, Hancock RE, Harrison JJ, Heeb S, Jelsbak L, Jia B, Kenna DT, Kidd TJ, Klockgether J, Lam JS, Lamont IL, Lewenza S, Loman N, Malouin F, Manos J, McArthur AG, McKeown J, Milot J, Naghra H, Nguyen D, Pereira SK, Perron GG, Pirnay JP, Rainey PB, Rousseau S, Santos PM, Stephenson A, Taylor V, Turton JF, Waglechner N, Williams P, Thrane SW, Wright GD, Brinkman FS, Tucker NP, Tümmler B, Winstanley C, Levesque RC. Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium. Front Microbiol 2015; 6: 1036.
Graeber SY, Hug MJ, Sommerburg O, Hirtz S, Hentschel J, Heinzmann A, Dopfer C, Schulz A, Mainz JG, Tümmler B, Mall MA. Intestinal Current Measurements Detect Activation of Mutant CFTR in Patients with Cystic Fibrosis with the G551D Mutation Treated with Ivacaftor. Am J Respir Crit Care Med 2015; 192: 1252-5.
Hilker R, Munder A, Klockgether J, Losada PM, Chouvarine P, Cramer N, Davenport CF, Dethlefsen S, Fischer S, Peng H, Schönfelder T, Türk O, Wiehlmann L, Wölbeling F, Gulbins E, Goesmann A, Tümmler B. Interclonal gradient of virulence in the Pseudomonas aeruginosa pangenome from disease and environment. Environ Microbiol 2015; 17: 29-46.
Merches K, Khairnar V, Knuschke T, Shaabani N, Honke N, Duhan V, Recher M, Navarini AA, Hardt C, Häussinger D, Tümmler B, Gulbins E, Futerman AH, Hoffmann D, Lang F, Lang PA, Westendorf AM, Lang KS. Virus-Induced Type I Interferon Deteriorates Control of Systemic Pseudomonas Aeruginosa Infection. Cell Physiol Biochem. 2015; 36: 2379-92.
Munder A, Tümmler B. Origins of cystic fibrosis lung disease. N Engl J Med 2015; 372: 1574.
Rademacher J, Schulz A, Hedtfeld S, Stanke F, Ringshausen F, Welte T, Tümmler B. Nasal potential difference of carriers of the W493R ENaC variant with non-cystic fibrosis bronchiectasis. Eur Respir J 2016; 47:322-4.
Schulz A, Tümmler B. Non-allergic asthma as a CFTR-related disorder. J Cyst Fibros. 2015 Oct 30.
Stanke, Frauke. The Contribution of the Airway Epithelial Cell to Host Defense. Mediators of inflammation 2015 (2015).
Wiehlmann L, Cramer N, Tümmler B. Habitat-associated skew of clone abundance in the Pseudomonas aeruginosa population. Environ Microbiol Rep. 2015; 7: 955-60.
Tümmler B (Hrsg) Mutation-specific therapies in cystic fibrosis – Current status and prospects. 2014, UNI-MED Verlag, Bremen, pp. 88.
Hilker R, Munder A, Klockgether J, Losada PM, Chouvarine P, Cramer N, Davenport CF, Dethlefsen S, Fischer S, Peng H, Schönfelder T, Türk O, Wiehlmann L, Wölbeling F, Gulbins E, Goesmann A, Tümmler B., Interclonal gradient of virulence in the Pseudomonas aeruginosa pangenome from disease and environment. Environ Microbiol. 2014 Aug 26. doi: 10.1111/1462-2920.12606.
Munder A, Tümmler B., Assessing Pseudomonas virulence using mammalian models: acute infection model. Methods Mol Biol. 2014;1149:773-91.
Munder A, Wölbeling F, Klockgether J, Wiehlmann L, Tümmler B. In vivo imaging of bioluminescent Pseudomonas aeruginosa in an acute murine airway infection model. Pathog Dis. 2014;72:74-7.
Stanke F, van Barneveld A, Hedtfeld S, Wölfl S, Becker T, Tümmler B. The CF-modifying gene EHF promotes p.Phe508del-CFTR residual function by altering protein glycosylation and trafficking in epithelial cells. Eur J Hum Genet. 2014;22:660-6.
Stanke F, van Barneveld A, Hedtfeld S, Wölfl S, Becker T, Tümmler B. The CF-modifying gene EHF promotes p.Phe508del-CFTR residual function by altering protein glycosylation and trafficking in epithelial cells. Eur J Hum Genet. 2014;22(5),660-666.
Davenport CF, Tümmler B. Advances in computational analysis of metagenome sequences. Environ Microbiol. 2013;15:1-5.
Junge S, Tümmler B. (2013) Mukoviszidose. Forum Sanitas 1:11-13.
Klockgether J, Miethke N, Kubesch P, Bohn YS, Brockhausen I, Cramer N, Eberl L, Greipel J, Herrmann C, Herrmann S, Horatzek S, Lingner M, Luciano L, Salunkhe P, Schomburg D, Wehsling M, Wiehlmann L, Davenport CF, Tümmler B. Intraclonal diversity of the Pseudomonas aeruginosa cystic fibrosis airway isolates TBCF10839 and TBCF121838: distinct signatures of transcriptome, proteome, metabolome, adherence and pathogenicity despite an almost identical genome sequence. Environ Microbiol. 2013;15:191-210.
Kolbe EW, Tamm S, Hedtfeld S, Becker T, Tümmler B, Stanke F. CLCA4 variants determine the manifestation of the cystic fibrosis basic defect in the intestine. Eur J Hum Genet. 013;21:691-4.
Stanke F, Tümmler B, Stuhrmann-Spangenberg M. Mukoviszidose – eine pleiotrope Ionenkanalerkrankung mit wesentlicher Lungenbeteiligung. Medgen 2013; 25:486-492.
Tümmler B. Mutation-specific therapy in cystic fibrosis: the earlier, the better. Lancet Respir Med. 2013;1:591-2.
Tümmler B. Mukoviszidose. Monatsschr Kinderheilkd 2013; 161:399-405.
Tümmler B. (2013) Zystische Fibrose. Mikrobiologie. In: von Mutius E, Gappa M, Eber E, Frey U (Hrsg.) Pädiatrische Pneumologie. Springer, Berlin, Heidelberg. S. 606 – 610.
von Kanel T, Stanke F, Weber M, Schaller A, Racine J, Kraemer R, Chanson M,
Tümmler B, Gallati S. Clinical and molecular characterization of the potential CF disease modifier syntaxin 1A. Eur J Hum Genet. 2013; 21:1462-6.
von Kanel T, Stanke F, Weber M, Schaller A, Racine J, Kraemer R, Chanson M, Tümmler B, Gallati S. Clinical and molecular characterization of the potential CF disease modifier syntaxin 1A. (2013) Eur J Hum Genet.
Kolbe, E.-W., Tamm, S., Hedtfeld, S., Becker, T., Tümmler, B., Stanke, F., CLCA4 variants determine the manifestation of the cystic fibrosis basic defect in the intestine, (2012), European Journal of Human Genetics, . Article in Press.
Becker, K.A., Henry, B., Ziobro, R., Tümmler, B., Gulbins, E., Grassmé, H.; Role of CD95 in pulmonary inflammation and infection in cystic fibrosis, (2012) Journal of Molecular Medicine, 90 (9), pp. 1011-1023.
Handschick, M., Hedtfeld, S., Tümmler, B., Frequency of the hyperactive W493R ENaC variant in carriers of a CFTR mutation, (2012) Journal of Cystic Fibrosis, 11 (1), pp. 53-55.
Van Barneveld, A., Zander, I., Hyde, R., Länger, F., Simon, A., Krüger, M., Ballmann, M., Derichs, N., Tümmler, B., Immunochemical analysis of mutant CFTR in lung explants, (2012) Cellular Physiology and Biochemistry, 30 (3), pp. 587-595.
Davenport, C.F., Tümmler, B., Advances in computational analysis of metagenome sequences, (2013) Environmental Microbiology, 15 (1), pp. 1-5.
Cramer, N., Wiehlmann, L., Ciofu, O., Tamm, S., Høiby, N., Tümmler, B., Molecular Epidemiology of Chronic Pseudomonas aeruginosa Airway Infections in Cystic Fibrosis, (2012) PLoS ONE, 7 (11), art. no. e50731.
Davenport, C.F., Neugebauer, J., Beckmann, N., Friedrich, B., Kameri, B., Kokott, S., Paetow, M., Siekmann, B., Wieding-Drewes, M., Wienhöfer, M., Wolf, S., Tümmler, B., Ahlers, V., Sprengel, F., Genometa - A fast and accurate classifier for short metagenomic shotgun reads, (2012) PLoS ONE, 7 (8), art. no. e41224.
Mainz, J.G., Hentschel, J., Schien, C., Cramer, N., Pfister, W., Beck, J.F., Tümmler, B., Sinonasal persistence of Pseudomonas aeruginosa after lung transplantation, (2012) Journal of Cystic Fibrosis, 11 (2), pp. 158-161.
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