Birkelbach B, Lutz D, Ruppert C, Henneke I, Lopez-Rodriguez E, Günther A, Ochs M, Mahavadi P, Knudsen L (2015): Linking progression of fibrotic lung remodeling and ultrastructural alterations of alveolar epithelial type II cells in the amiodarone mouse model. Am J Physiol (Lung Cell Mol Physiol) 309:L63-L75
Brandenberger C, Ochs M, Mühlfeld C (2015): Assessing particle and fiber toxicology in the respiratory system: the stereology toolbox. Part Fibre Toxicol 12:35:1-15
Grothausmann R, Kellner M, Heidrich M, Lorbeer RA, Ripken T, Meyer H, Kühnel MP, Ochs M, Rosenhahn B (2015): Method for 3D airway topology extraction. Comput Math Meth Med 127010:1-7
Holm AT, Wulf-Johansson H, Hvidsten S, Jorgensen PT, Schlosser A, Pilecki B, Ormhoj M, Moeller JB, Johannsen C, Baun C, Andersen T, Schneider JP, Hegermann J, Ochs M, Götz A, Schulz H, Hrabe de Angelis M, Vestbo J, Holmskov U, Sorensen GL (2015): Characterization of spontaneous air space enlargement in mice lacking microfibrillar-associated protein 4. Am J Physiol (Lung Cell Mol Physiol) 308:L1114-L1124
Katsirntaki K, Mauritz C, Olmer R, Schmeckebier S, Sgodda M, Puppe V, Duerr J, Eggenschwiler R, Schubert SC, Schmiedl A, Ochs M, Cantz T, Mall M, Salwig I, Szibor M, Rathert C, Martens A, Braun T, Martin U (2015): Bronchoalveolar sublineage specification of pluripotent stem cells: effect of dexamethasone plus cAMP-elevating agents and keratinocyte growth factor. Tissue Eng A 21:669-682
Kellner M, Wehling J, Warnecke G, Heidrich M, Izykowski N, Vogel-Claussen J, Lorbeer RA, Antonopoulos GC, Janciauskiene S, Grothausmann R, Knudsen L, Ripken T, Meyer H, Kreipe H, Ochs M, Jonigk D, Kühnel MP (2015): Correlating 3D morphology with molecular pathology: fibrotic remodelling in human lung biopsies. Thorax 70:1197-1198
Knudsen L, Atochina-Vasserman E, Massa CB, Birkelbach B, Guo CJ, Scott P, Haenni B, Beers MF, Ochs M, Gow AJ (2015): The role of inducible nitric oxide synthase (NOS2) for interstitial remodeling of alveolar septa in surfactant protein D (SP-D) deficient mice. Am J Physiol (Lung Cell Mol Physiol) 309:L959-L969
Lutz D, Gazdhar A, Lopez-Rodriguez E, Ruppert C, Mahavadi P, Günther A, Klepetko W, Bates JH, Smith B, Geiser T, Ochs M, Knudsen L (2015): Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis. Am J Respir Cell Mol Biol 52:232-243
Mahavadi P, Knudsen L, Venkasetan S, Henneke I, Hegermann J, Wrede C, Ochs M, Ahuja S, Chillappagari S, Ruppert C, Seeger W, Korfei M, Günther A (2015): Regulation of macroautophagy in amiodarone-induced pulmonary fibrosis. J Pathol Clin Pathol 1:252-263
McDonough JE, Knudsen L, Wright AC, Elliott WM, Ochs M, Hogg JC (2015): Regional differences in alveolar density in the human lung are related to lung height. J Appl Physiol 118:1429-1434
Mühlfeld C, Hegermann J, Wrede C, Ochs M (2015): A review of recent developments and applications of morphometry/stereology in lung research. Am J Physiol (Lung Cell Mol Physiol) 309:L526-L536
Schneider JP, Pedersen L, Mühlfeld C, Ochs M (2015): Staining histological lung sections with Sudan Black B or Sudan III - An easy method for secure automated identification of alveolar epithelial type II cells. Acta Histochem 117:675-680
Willführ A, Brandenberger C, Piatkowski T, Grothausmann R, Nyengaard JR, Ochs M, Mühlfeld C (2015): Estimation of the number of alveolar capillaries by the Euler number (Euler-Poincaré characteristic). Am J Physiol (Lung Cell Mol Physiol) 309:L1286-L1293
Herrmann G, Knudsen L, Madershahian N, Mühlfeld C, Frank K, Rahmanian P, Wahlers T, Wittwer T, Ochs M (2014): Effects of exogenous surfactant on the non-heart-beating donor lung graft in experimental lung transplantation - a stereological study. J Anat 224:594-602.
Johnson L, Montgomery J, Schneider JP, Townsend H, Ochs M, Singh B (2014): Morphometric examination of the equine adult and foal lung. Anat Rec 297:1950-1962.
Katsirntaki K, Mauritz C, Olmer R, Schmeckebier S, Sgodda M, Puppe V, Duerr J, Eggenschwiler R, Schubert SC, Schmiedl A, Ochs M, Cantz T, Mall M, Salwig I, Szibor M, Rathert C, Martens A, Braun T, Martin U (2014): Bronchoalveolar sublineage specification of pluripotent stem cells: effect of dexamethasone plus cAMP-elevating agents and keratinocyte growth factor. Tissue Eng A 2014 Oct 15.
Knudsen L, Atochina-Vasserman EN, Guo CJ, Scott P, Haenni B, Beers MF, Ochs M, Gow A (2014): NOS2 is critical to the development of emphysema in Sftpd deficient mice but does not affect surfactant homeostasis. PLoS One 9:e85722:1-10.
Körner C, Kuchenbuch T, Pfeil U, Jung K, Padberg W, Kummer W, Mühlfeld C, Grau V (2014): Low-dose adrenomedullin-2/intermedin(8-47) reduces pulmonary ischemia/reperfusion injury. Peptides 62:49-54.
Lutz D, Gazdhar A, Lopez-Rodriguez E, Ruppert C, Mahavadi P, Günther A, Klepetko W, Bates JH, Smith B, Geiser T, Ochs M, Knudsen L (2015): Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis. Am J Respir Cell Mol Biol;52(2):232-43.
Ochs M (2014): Estimating structural alterations in animal models of lung emphysema. Is there a gold standard? Ann Anat 196:26-33.
Schneider JP, Ochs M (2014): Alterations of mouse lung tissue dimensions during processing for morphometry - a comparison of methods. Am J Physiol (Lung Cell Mol Physiol) 306:L341-L350.
Tahedl D, Wirkes A, Tschanz SA, Ochs M, Mühlfeld C (2014): How common is the lipid body-containing interstitial cell in the mammalian lung? Am J Physiol (Lung Cell Mol Physiol) 307:L386-394.
Winkler C, Bahlmann O, Viereck J, Knudsen L, Wedekind D, Hoymann HG, Madsen J, Thum T, Hohlfeld JM, Ochs M (2014): Impact of a Met(11)Thr single nucleotide polymorphism of surfactant protein D on allergic airway inflammation in a murine asthma model. Exp Lung Res 40:154-163.
Lutz D, Gazdhar A, Lopez-Rodriguez E, Mahavadi P, Ruppert C, Günther A, Klepetko W, Smith B, Bates J, Geiser T, Ochs M and Knudsen L (2015) Alveolar derecruitment and collapse induration as crucial mechanisms in lung injury and fibrosis. Am J Respir Cell Mol Biol, 52(2): 232-43.
Mühlfeld C, Knudsen L, Ochs M (2013): Stereology and morphometry of lung tissue. Meth Mol Biol 931:367-390.
Schneider JP, Ochs M (2013): Stereology of the lung. Meth Cell Biology 113:257-294.
Adam RJ, Michalski AS, Bauer C, Abou Alaiwa MH, Gross TJ, Awadalla MA, Bouzek DC, Gansemer ND, Taft PJ, Hoegger MJ, Diwakar A, Ochs M, Reinhardt JM, Hoffman EA, Beichel RR, Meyerholz DK, Stoltz DA (2013): Air trapping and airway obstruction in newborn cystic fibrosis pigs. Am J Respir Crit Care Med 188:1434-1441.
Gazdhar A, Temuri A, Knudsen L, Gugger M, Schmid RA, Ochs M, Geiser T. Targeted gene transfer of hepatocyte growth factor to alveolar type II epithelial cells reduces lung fibrosis in rats. (2013) Human Gene Therapy, 24 (1), pp. 105-116.
Gazdhar A, Susuri N, Hostettler K, Gugger M, Knudsen L, Roth M, Ochs M, Geiser T: HGF expressing stem cells in usual interstitial pneumonia originate from the bone marrow and are antifibrotic. (2013) PLoS ONE, 8 (6), art. no. e65453.
Knudsen L, Ochs K, Boxler L, Tornoe I, Sorensen G, Mackay RM, Clark H, Holmskov U, Ochs M, Madsen J: Surfactant protein D (SP-D) deficiency is attenuated in humanized mice expressing the Met(11)Thr short nucleotide polymorphism of SP-D: implications for surfactant metabolism in the lung. (2013) J Anat 223:581-592.
Mühlfeld C, Schipke J, Schmidt A, Post H, Pieske B, Sedej S: Hypoinnervation is an early event in left ventricular hypertrophy and failure due to experimental pressure overload. (2013) J Anat 222:634-644.
Patra C, van Amerongen MJ, Ghosh S, Ricciardi F, Sajjad A, Novoyatleva T, Mogha A, Monk KR, Mühlfeld C, Engel FB.: Adhesion G protein-coupled receptor GPR126 function is organ-specific. (2013) Proc Natl Acad Sci USA 110:16898-16903.
Schmeckebier S, Mauritz C, Katsirntaki K, Sgodda M, Puppe V, Duerr J, Schubert S, Schmiedl A, Lin Q, Palacek J, Draeger G, Ochs M, Zenke M, Cantz T, Mall M, Martin U: Keratinocyte growth factor and dexamethasone plus elevated cAMP levels synergistically support pluripotent stem cell differentiation into alveolar epithelial type II cells. (2013) Tissue Eng A 19:938-951.
Vasilescu D, Klinge C, Knudsen L, Yin L, Wang G, Weibel ER, Ochs M, Hoffman EA: Stereological assessment of mouse lung parenchyma via non-destructive multi-scale micro CT imaging validated by light microscopic histology. (2013) J Appl Physiol 114:716-724.
Wittwer T, Madershahian N, Rahmanian P, Choi YH, Neef K, Frank K, Müller-Ehmsen J, Ochs M, Mühlfeld C, Wahlers T (2013): Surfactant application in experimental lung transplantation. J Heart Lung Transplant 32:355-359.
Ochs M. Rebuilding the lung: signals for a complex architectural task. (2013) J Appl Physiol, 114 (8), pp. 959-60.
Ochs M, Mühlfeld C. Quantitative microscopy of the lung: a problem-based approach. Part 1: basic principles of lung stereology. (2013) Am J Physiol Lung Cell Mol Physiol, 305 (1), pp. 15-22.
Muehlfeld C, Ochs M. Quantitative microscopy of the lung: a problem-based approach. Part 2: stereological parameters and study designs in various diseases of the respiratory tract. Am J Physiol Lung Cell Mol Physiol. 305 (3), pp. 205-21.
Vasilescu DM, Klinge C, Knudsen L, Yin L, Wang G, Weibel ER, Ochs M, Hoffman EA. Stereological assessment of mouse lung parenchyma via nondestructive, multiscale micro-CT imaging validated by light microscopic histology. (2013) J Appl Physiol, 114 (6), pp. 716-24.
Vasilescu, D.M., Gao, Z., Saha, P.K., Yin, L., Wang, G., Haefeli-Bleuer, B., Ochs, M., Weibel, E.R., Hoffman, E.A., Assessment of morphometry of pulmonary acini in mouse lungs by nondestructive imaging using multiscale microcomputed tomography, (2012) Proceedings of the National Academy of Sciences of the United States of America, 109 (42), pp. 17105-17110.
Kellner, M., Heidrich, M., Beigel, R., Lorbeer, R.-A., Knudsen, L., Ripken, T., Heisterkamp, A., Meyer, H., Kühnel, M.P., Ochs, M., Imaging of the mouse lung with scanning laser optical tomography (SLOT), (2012) Journal of Applied Physiology, 113 (6), pp. 975-983.
Leuenberger, A., Gazdhar, A., Herrmann, G., Ochs, M., Geiser, T., Knudsen, L., Cell-specific expression of human HGF by alveolar type II cells induces remodeling of septal wall tissue in the lung: A morphometric study, (2012) Journal of Applied Physiology, 113 (5), pp. 799-807.
Frenzel, E., Korenbaum, E., Hegermann, J., Ochs, M., Koepke, J., Koczulla, A.R., Welte, T., Köhnlein, T., Janciauskiene, S., Does Augmentation with Alpha1-Antitrypsin Affect Neutrophil Extracellular Traps Formation?, (2012) International Journal of Biological Sciences, 8 (7).
Steinwede, K., Maus, R., Bohling, J., Voedisch, S., Braun, A., Ochs, M., Schmiedl, A., Länger, F., Gauthier, F., Roes, J., Welte, T., Bange, F.C., Niederweis, M., Bühling, F., Maus, U.A., Cathepsin G and neutrophil elastase contribute to lung-protective immunity against mycobacterial infections in mice, (2012) Journal of Immunology, 188 (9), pp. 4476-4487.
Knudsen, L., Boxler, L., Mühlfeld, C., Schaefer, I.-M., Becker, L., Bussinger, C., Von Stietencron, I., Madershahian, N., Richter, J., Wahlers, T., Wittwer, T., Ochs, M., Lung preservation in experimental ischemia/reperfusion injury and lung transplantation: A comparison of natural and synthetic surfactants, (2012) Journal of Heart and Lung Transplantation, 31 (1), pp. 85-93.
Vasilescu, D.M., Knudsen, L., Ochs, M., Weibel, E.R., Hoffman, E.A., Optimized murine lung preparation for detailed structural evaluation via micro-computed tomography, (2012) Journal of Applied Physiology, 112 (1), pp. 159-166.
Renne J, Lauermann P, Hinrichs J, Schonfeld C, Sorrentino S, Gutberlet M, Jakob P, Wacker F, Vogel-Claussen J. Clinical use of oxygen-enhanced t mapping mri of the lung: Reproducibility and impact of closed versus loose fit oxygen delivery system. Journal of magnetic resonance imaging : JMRI 2013.
Schonfeld C, Cebotari S, Voskrebenzev A, Gutberlet M, Hinrichs J, Renne J, Hoeper MM, Olsson KM, Welte T, Wacker F, Vogel-Claussen J. Performance of perfusion-weighted fourier decomposition mri for detection of chronic pulmonary emboli. Journal of magnetic resonance imaging : JMRI 2014.
Hueper K, Parikh MA, Prince MR, Schoenfeld C, Liu C, Bluemke DA, Dashnaw SM, Goldstein TA, Hoffman EA, Lima JA, Skrok J, Zheng J, Barr RG, Vogel-Claussen J. Quantitative and semiquantitative measures of regional pulmonary microvascular perfusion by magnetic resonance imaging and their relationships to global lung perfusion and lung diffusing capacity: The multiethnic study of atherosclerosis chronic obstructive pulmonary disease study. Investigative radiology 2013;48:223-230.
Hinrichs J, Schaumann F, Renne J, Schonfeld C, Faulenbach C, Winkler C, Gutberlet M, Krug N, Wacker F, Hohlfeld JM, Vogel-Claussen J. Phase-contrast mri for detection of mild systemic hemodynamic response after segmental allergen challenge in asthmatic patients. Academic radiology 2014;21:994-1001.
Shehata ML, Basha TA, Hayeri MR, Hartung D, Teytelboym OM, Vogel-Claussen J. Mr myocardial perfusion imaging: Insights on techniques, analysis, interpretation, and findings. Radiographics : a review publication of the Radiological Society of North America, Inc 2014;34:1636-1657.
Shehata ML, Harouni AA, Skrok J, Basha TA, Boyce D, Lechtzin N, Mathai SC, Girgis R, Osman NF, Lima JA, Bluemke DA, Hassoun PM, Vogel-Claussen J. Regional and global biventricular function in pulmonary arterial hypertension: A cardiac mr imaging study. Radiology 2013;266:114-122.
Vogel-Claussen J, Skrok J, Shehata ML, Singh S, Sibley CT, Boyce DM, Lechtzin N, Girgis RE, Mathai SC, Goldstein TA, Zheng J, Lima JA, Bluemke DA, Hassoun PM. Right and left ventricular myocardial perfusion reserves correlate with right ventricular function and pulmonary hemodynamics in patients with pulmonary arterial hypertension. Radiology 2011;258:119-127.
Skrok J, Shehata ML, Mathai S, Girgis RE, Zaiman A, Mudd JO, Boyce D, Lechtzin N, Lima JA, Bluemke DA, Hassoun PM, Vogel-Claussen J. Pulmonary arterial hypertension: Mr imaging-derived first-pass bolus kinetic parameters are biomarkers for pulmonary hemodynamics, cardiac function, and ventricular remodeling. Radiology 2012;263:678-687.
Vogel-Claussen J, Renne J, Hinrichs J, Schonfeld C, Gutberlet M, Schaumann F, Winkler C, Faulenbach C, Krug N, Wacker FK, Hohlfeld JM. Quantification of pulmonary inflammation after segmental allergen challenge using turbo-inversion recovery-magnitude magnetic resonance imaging. American journal of respiratory and critical care medicine 2014;189:650-657.
Renne J, Hinrichs J, Schonfeld C, Gutberlet M, Winkler C, Faulenbach C, Jakob P, Schaumann F, Krug N, Wacker F, Hohlfeld JM, Vogel-Claussen J. Noninvasive quantification of airway inflammation following segmental allergen challenge with functional mr imaging: A proof of concept study. Radiology 2014:132607.
Dettmer S, Peters L, de Wall C, Schaefer-Prokop C, Schmidt M, Warnecke G, Gottlieb J, Wacker F, Shin HO. Bronchial wall measurements in patients after lung transplantation: Evaluation of the diagnostic value for the diagnosis of bronchiolitis obliterans syndrome. PloS one 2014;9:e93783.
Vogel-Claussen J, Renne J, Hinrichs J, Schönfeld C, Gutberlet M, Schaumann F, Winkler C, Faulenbach C, Krug N, Wacker FK, Hohlfeld JM. Quantification of Pulmonary Inflammation after Segmental Allergen Challenge Using TIRM Magnetic Resonance Imaging. Am J Respir Crit Care Med. 2014 Jan 8.
Renne J, Lauermann P, Hinrichs J, Schönfeld C, Sorrentino S, Gutberlet M, Jakob P, Wacker F, Vogel-Claussen J. Clinical use of oxygen-enhanced T1 mapping MRI of the lung: Reproducibility and impact of closed versus loose fit oxygen delivery system. J Magn Reson Imaging. 2013 Dec 12. doi: 10.1002/jmri.24535. [Epub ahead of print]
Hinrichs J, Bengel F, Wacker F, Vogel-Claussen J. Lung infarction--a diagnostic challenge in the oncologic patient? Rofo. 2013 Oct;185(10):915-9.
Woodard PK, White RD, Abbara S, Araoz PA, Cury RC, Dorbala S, Earls JP, Hoffmann U, Hsu JY, Jacobs JE, Javidan-Nejad C, Krishnamurthy R, Mammen L, Martin ET, Ryan T, Shah AB, Steiner RM, Vogel-Claussen J, White CS. ACR Appropriateness Criteria Chronic Chest Pain-Low to Intermediate Probability of Coronary Artery Disease. J Am Coll Radiol. 2013 May;10(5):329-34.
Thomashow MA, Shimbo D, Parikh MA, Hoffman EA, Vogel-Claussen J, Hueper K, Fu J, Liu C-Y, Bluemke DA, Ventetuolo CE, Doyle MF, Barr RG. Endothelial microparticles in mild COPD and emphysema: the MESA COPD Study. Am J Respir Crit Care Med. 2013 Apr 19 188(1):60-8.
Roentgen P, Vogel-Claussen J, Schäfer A, Issam I, Bauersachs J. Multimodality cardiac imaging for diagnosing rare causes of cardiac arrest. Intensive Care Med. 2013 May;39(5):960-1.
Napp LC, Luesebrink U, Vogel-Claussen J, Bauersachs J, Roentgen P. Two's company double-chambered right ventricle. Circulation. 2013 Mar 5;127(9):e469-70.
Hueper K, Parikh MA, Prince MR, Schoenfeld C, Liu C, Bluemke DA, Dashnaw SM, Goldstein TA, Hoffman EA, Lima JA, Skrok J, Zheng J, Barr RG, Vogel-Claussen J. Quantitative and semiquantitative measures of regional pulmonary microvascular perfusion by magnetic resonance imaging and their relationships to global lung perfusion and lung diffusing capacity: the multiethnic study of atherosclerosis chronic obstructive pulmonary disease study. Invest Radiol. 2013 Apr;48(4):223-30.
Shehata ML, Harouni AA, Skrok J, Basha TA, Boyce D, Lechtzin N, Mathai SC, Girgis R, Osman NF, Lima JA, Bluemke DA, Hassoun PM, Vogel-Claussen J. Regional and global biventricular function in pulmonary arterial hypertension: a cardiac MR imaging study. Radiology. 2013 Jan;266(1):114-22.
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