Scientists in the BREATH research network make a significant contribution to DPLD research, particularly in the field of pulmonary fibrotic research. Particular attention is paid to the validation of microCT imaging as a non-invasive tool for the characterization of the course of disease of pulmonary fibrosis in preclinical animal models. In addition, research is carried out on the role of antifibrotic protease cathepsin K and the general course of disease of pulmonary fibrosis.