Februar 19, 2018BREATH involved in successful international study for new treatment approaches for CF
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The phase 3 clinical study EXPAND, recently published in the prestigious New England Journal of Medicine, demonstrates the efficacy and safety of a novel CFTR-modulating combination therapy for the treatment of patients with cystic fibrosis (CF) with heterozygous Phe508del mutation and an additional mutation with residual CFTR function [1]. With Dr. Felix Ringshausen, senior physician at the clinic of pulmonology and head of study at the Hannover Medical School, BREATH, the Hannover site of the German Center for Lung Diseases (DZL), is the largest European center involved in this international drug study.
January 29, 2018DZL-funded clinical study shows direct influence of the drug combination Lumacaftor/Ivacaftor on CFTR function for the first time
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Cystic fibrosis is the most common autosomal recessive hereditary disease in Europe. Since the identification of the disease-causing gene CFTR in 1989, a causal therapy has been researched. The malfunction is caused by autosomal recessive inherited mutations of the CFTR gene, whereby the specific mechanism of the malfunction is dependent on the mutation class. Until just a few years ago, solely symptomatic treatment of patients was possible.
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December 8, 2017Since the early days of DZL, the group of Prof. Dr. Axel Haverich at the DZL-site BREATH have been “on the way to an implantable, artificial lung”. Recently the BREATH scientists have successfully applied for additional funds in a 7-digit amount. Their research will be supported through the Focus Program (Schwerpunktprogramm) SPP 2014 of the German Research Society (DFG) over the next 6 years.
October 30, 2017Increase their cooperation: rheumatology and pneumology
Expert Forum Rheumatology and Pneumology – frequently missed co-morbidities
On October 25 Prof. Dr. Tobias Welte, Director of the Department of Respiratory Medicine at MHH, and Prof. Dr. Reinhold E. Schmidt, Director of the Department of Immunology and Rheumatology, invited practitioners and physicians from regional hospitals to their first joint experts’ forum.
More than 50 participants caught up on the connection between rheumatologic and pneumologic diseases.
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September 15, 2017pedCAPNETZ – Multicenter cohorts for community-acquired pneumonia in childhood and youth
Community-Acquired Pneumonia (CAP) in childhood and adolescence is, according to the WHO, one of the most common causes of death in children under 5 years of age. Improvement in the vaccination situation and good treatment possibilities have led to a significant reduction in mortality in developing countries. However, pneumonia is still responsible for 20% of hospital admissions.
September 4, 2017A panel of experts develops a consensus-based statement on exacerbations in patients with bronchiectasis
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The time until the first exacerbation as well as the number of exacerbations over a certain period of time is used as a crucial endpoint in many clinical studies on bronchiectasis. When a change in the symptoms is considered to be a deterioration and therefore an exacerbation, has up to now, however, been variously defined. Standardization of the criteria is therefore essential for valid comparison of future studies. A consensus paper on this matter will shortly be published in the European Respiratory Journal.
August 18, 2017PhD student Berenice Rath reports on the15th Annual Retreat “Molecular Biology and Medicine of the Lung”
The 15th Annual Retreat of the international graduate program „Molecular Biology and Medicine of the Lung“ (MBML) was held from 12 - 14 July, 2017.
July 18, 2017
The German Council of Science and Humanities praises the German Centers for Health Research (DZG)
The German Centers for Health Research (Deutsche Zentren für Gesundheitsforschung - DZG), among them the German Center for Lung Research (DZL), have been praised in the highest tones by the German Council of Science and Humanities (Wissenschaftsrat). After a thorough evaluation procedure the Council confirms that the DZGs are a valid model to promote translational research in specific disease areas.
In its official evaluation the German Council of Science and Humanities, which advises the Federal Government of Germany as well as its States, certifies that the six centers play an important role in the German science system and recommend their further development.
July 3, 2017
Press releaseMulticentric Lung Study CHANGE MRI - Successful first year
The CHANGE MRI study was successfully launched with a joint kick-off meeting in Hannover (press release Kick-off Meeting 2016) almost to the day one year ago. Now the initiation of the study was completed at all centers and the research project started.
June 26, 2017Balloon pulmonary angioplasty for patients with inoperable chronic thromboembolic pulmonary hypertension
Scientists at the German Center for Lung Research successfully establish a treatment method from Japan
The first mass screening in Germany using balloon pulmonary angioplasty (BPA) for patients with inoperable chronic thromboembolic pulmonary hypertension (CTEPH) was recently published in the high-ranking European Respiratory Journal.
A total of 266 interventions in 56 patients were carried out at two sites of the German Center for Lung Research (DZL) – at Hannover Medical School (MHH) and at the Kerckhoff Clinic in Bad Nauheim. In Bad Nauheim, cardiologists from the German Centre for Cardiovascular Research (DZHK) were also involved.
June 15, 2017Adolf Windorfer Prize awarded to BREATH working group
The microbial metagenome of the lower airways
Dr. Patricia Morán Losada, scientist at the Clinic for Pediatric Pneumology and Neonatology at Hannover Medical School, won the Adolf Windorfer Prize for Research on Cystic Fibrosis. The prize is endowed with 5 000 Euros and was awarded during the annual conference of the Mukoviszidose e.V., the German CF Association in May 2017.
Dr. Losada received this prize for her publication „The cystic fibrosis lower airways microbial metagenome“, which she conducted in the group led by Professor Dr. Tümmler. The work was partially financed by the Mukoviszidose e.V., while the main portion of the budget was contributed by the German Center for Lung Research (DZL). Professor Tümmler’s group is part of the DZL at its partner site BREATH (Biomedical Research in Endstage and Obstructive Lung Disease) in Hannover.
Publication:
The cystic fibrosis lower airways microbial metagenome
Moran Losada P, Chouvarine P, Dorda M, Hedtfeld S, Mielke S, Schulz A, Wiehlmann L, Tümmler B
ERJ Open Res. 2016 May 9;2(2). pii: 00096-2015. eCollection 2016 Apr.
May 22, 20174th Seminar for patients with bronchiectasis took place at Hannover Medical School
On May 13 the 4th patient seminar for patients with bronchiectasis took place at Hannover Medical School (MHH). As in previous years the seminar was fully booked well in advance, because due to the practical parts of the seminar it was only possible to admit 50 patients plus their relatives.
The two bronchiectasis specialists of the Department for Respiratory Medicine, Dr. Jessica Rademacher and Dr. Felix Ringshausen, who have been taking care of bronchiectasis patients at MHH for many years, provided latest news and finding on the diagnosis and therapy for bronchiectasis, as well as about the German Bronchiectasis Registry PROGNOSIS. PROGNOSIS was founded in 2015, mainly due to the engagement of these two experts.
May 15, 2017The Hannover Unified Biobank (HUB) is part of the German Biobank Alliance (GBA)
Since the 1st of May 2017, eleven German biobank sites have united to form the German Biobank Alliance (GBA). This paves the way for a national and Europe-wide biosamples and data exchange between biobanks. The central biobank of the Hannover Medical School (HUB), that also hosts the biobank of the Hannover site (BREATH) of the German Center for Lung Research, is one of the partners in the network.
„The German biobanks engage in a ground-breaking common initiative, which provides a basis for a new generation of Europe-wide cross-linked biobanks” explained the chairman of the Scientific Advisory Board of the initiative, Prof. Fay Betsou. The Federal Ministry for Education and Research (BMBF) has funded the biobank alliance with 14.4 Mio Euros until 2020.
April 27, 2017„Lung Fibrosis – an extremely diverse disease“
3rd Patient Seminar on Lung Fibrosis with record attendance
On April 8th, Professor Dr. Antje Prasse and her team from the Lung Fibrosis Outpatient Clinic at Hannover Medical School presented the 3rd Patient Seminar on Lung Fibrosis.
Since Professor Prasse joined the MHH in the summer of 2014, the number of patients treated in her outpatient clinic has increased to 350. It was therefore not astonishing that close to 100 patients and their relatives attended the latest patient seminar.
In addition to presentations by Professor Prasse about the diagnosis and therapy of lung fibrosis, Dr. Mark Kuehnel, a scientist from the Institute of Pathology at the MHH, talked about the latest imaging technologies and showed how these can make the delicate structure of the lung visible in 3D moving images.
March 24, 2017Marius Hoeper receives Oskar Medicine Award 2016
During this year’s conference of the German Respiratory Society (DGP), Prof. Dr. Marius Hoeper, senior physician of the Department for Respiratory Medicine at Hannover Medical School and scientist of the German Center for Lung Research (DZL), received the Oskar Medicine Award 2016 for his game-changing research in the field of pulmonary hypertension.
March 23, 2017Change in management at Fraunhofer ITEM
After 21 years of successful leadership, Professor Uwe Heinrich ceded his position as Executive Director of Fraunhofer ITEM to Professor Norbert Krug as of January 1, 2017.
read more...
(on homepage of the Fraunhofer ITEM)
March 22, 2017Workshop »Models of Lung Disease« 2017
On January 19 and 20, 2017, the 16th Fraunhofer seminar “Models of Lung Disease” was held in the Clinical Research Center (CRC) Hannover. It was organized once again by Fraunhofer ITEM in cooperation with the German Center for Lung Research (DZL). With over 130 people from 15 countries, this year’s seminar was booked out. Renowned international experts in translational lung research from industry and academia got together for the 16th time to discuss new developments in experimental lung research and compare different models and approaches. The program was finalized by several guided tours offered by Fraunhofer ITEM to a variety of its non-clinical and clinical departments.
March 15, 2017Special Issue “Development, remodelling and regeneration of the lung” with DZL expertise recently published
In March 2017, a special issue of the scientific journal Cell and Tissue Research with the title “Development, remodeling and regeneration of the lung” was published, with review articles about many important, up-to-date topics on lung research. The two professors Dr. Matthias Ochs and Dr. Christian Muehlfeld, both scientists within German Center for Lung Research (DZL) at the partner site BREATH, Biomedical Reserach in Endstage and Obstructive Lung Disease Hannover, oversaw the compilation of this special issue as guest editors.
February 14, 2017DZL scientist supports Kartagener Syndrom and Primary Ciliary Dyskinesia e.V.
Dr. med. Felix Ringshausen, DZL scientist at BREATH and member of the board of the German Bronchiectasis Registry PROGNOSIS, has been appointed to the Medical Advisory Board of the patient organization Kartagener Syndrom and Primary Ciliary Dyskinesia (PCD) e.V. in January 2017.
February 10, 2017
Record number of participants at the 6th DZL Annual Meeting in Munich
About 470 scientists, physicians and young researchers met together for the 6th internal annual meeting of the German Center for Lung Research on January 30 and 31, 2017 in Munich - a new record number of participants since the DZL has been founded.
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20. Januar 2017PROGNOSIS becomes associate partner of the German Center for Lung Research
At the beginning of this year, the Prospective German Non-CF-Bronchiectasis Registry (PROGNOSIS) and the German Center for Lung Research (DZL e.V.) signed a cooperation agreement through which PROGNOSIS officially became "associate partner of the DZL".
January 17, 2017Interview with Prof. Dr. Tobias Welte and the German Medical Association for Tobacco Prevention and Education Against Tobacco (an initiative of Medical Association Tobacco Prevention)
January 6, 2017New start of the PhD lecture series "Pneumology for Lung Researchers".
December 15, 2016German Center for Lung Research: fighting successfully against lung diseases for 5 years
The German Center for Lung Research, founded in 2011, looks back on five years of successful research in its fight against lung diseases...
December 1, 2016The DZL presented research results at the 19th German Cystic Fibrosis Conference
From November 17-19, the 19th German Cystic Fibrosis Conference took place in the Congress Center Würzburg. More than 800 participants from different professions, all of them involved in the treatment of patients with cystic fibrosis, discussed the latest research findings, the clinical implementation of therapies and other aspects of the disease. One of the main topics of the conference was the research program of the German Center for Lung Research (DZL) conducted in the field of cystic fibrosis.
November 21, 2016Autumn Meeting of the German Respiratory Society (DGP) in Hannover
The Cell Biology Section and Infectiology and Tuberculosis Section of the German Respiratory Society (DGP) held their Autumn Meeting at the Clinical Research Center in Hannover on 11 and 12 November. For many years, this annual meeting has offered young scientists a forum for the presentation of their own results and the opportunity to share information with each other.
October 24, 2016This is the age of bronchiectasis – First World Bronchiectasis Conference took place in Hannover
Bronchiectasis is the pathological end result of a number of heterogeneous disease processes. The vicious circle hypothesis proposes that impaired host defences lead to persistent bacterial infection which stimulates chronic neutrophilic inflammation. This together with bacterial products damages lung tissue, further impairing the defences, and perpetuating the circle.
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September 22, 2016Tobias Welte elected Vice-President of the European Respiratory Society (ERS)
Prof. Dr. Tobias Welte, Board Member of the German Center for Lung Research (DZL) and Director of the BREATH site, was elected Vice-President of the European Respiratory Society (ERS) on 6 September 2016. Following the one-year post as Vice-President of the ERS, he will take on the position of ERS President Elect from September 2017 and then ERS President from September 2018 to September 2019.
With numerous presentations, further award winners and its own information stand, the German Center for Lung Research was represented once again this year at the International Congress of the European Respiratory Society.
Article in German
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August 31, 2016DFG sponsors the establishment of a scientific database of drugs for cystic fibrosis
Bonn, 30 August 2016. Researchers working with Associate Professor (PD) Dr. Frauke Stanke, Hannover Medical School, and Dr. Manuel Manfred Nietert, University Medical Center Göttingen, are currently developing a database of drugs for cystic fibrosis. The database, called CandActCFTR, aims to focus on the research status of substances that have an effect on the cystic fibrosis transmembrane conductance regulator (CFTR) channel. The Mucoviscidosis Institute has co-initiated the project and will promote the use of the database in the research community. The project will be sponsored by the German Research Foundation (DFG) initially for two years with the amount of 332,000 €.
Article in English
July 6, 2016
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On Monday, June 20, 2016, the kick-off meeting of the new clinical trial CHANGE-MRI took place at Hannover Medical School, the Hannover site of the German Center for Lung Research (BREATH). Partners of the DZL sites Giessen, Heidelberg and Munich participated in the meeting, as well as the partners from Sheffield (UK).
CHANGE-MRI is a diagnostic study for a new method of displaying CTEPH-typical hypoperfusion of the lung. The aim of the study is to investigate whether the radiation-free magnetic resonance imaging system (MRI) is equivalent to established methods for the diagnosis of CTEPH. It is financed and performed by the German Center for Lung Research and the University of Sheffield.
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June 27, 2016Combating cystic fibrosis: MHH researchers coordinate European network
The European Union awards funding of 1.2 million euros to the Network for Rare Diseases
In Germany, one in 3,000 children is born with cystic fibrosis (CF). The European Network for Rare Diseases (INSTINCT) is dedicated to searching for new medications to treat this rare condition. Starting on 1 June 2016, eight partner organizations from Germany, Italy, Canada, the Netherlands and Portugal are conducting research within the E-Rare Network for Rare Diseases to find new combinations of active substances. The project’s coordinator is Professor Ulrich Martin of the Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO) and the Department of Cardiac, Thoracic, Transplantation and Vascular Surgery (HTTG) at Hannover Medical School (MHH), who is also PI at the German Center for Lung Research (DZL).
May 10, 2016A group of students visits the Pediatric Research Center (PFZ) as part of the seminar course „Medicine in the focus of research“
Student report – Visit to the PFZ at the MHH
On 16 March, with our teacher, Frau Schmidt, we visited the Pediatric Research Center (PFZ) as part of our biology seminar course, to learn more about cystic fibrosis. As we were already studying this subject closely in the seminar course „Medicine in the focus of research“, it made sense to take this opportunity to visit the Center.
Article in German
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May 3, 2016Longed for support for „Big Data“ projects realized
With David S. DeLuca, computational scientist with a doctoral degree, the scientific network BREATH, Member of the German Center for Lung Research, was able to recruit a specialist in bio informatics with international experience. Dr. DeLuca started his assignment at Hannover Medical School on April 1 and is looking forward to supporting DZL projects which involve big data sets.
April 12, 2016Paediatric Pneumology: PD Dr. Anna-Maria Dittrich receives Research Award
PD Dr. Anna-Maria Dittrich, scientist at DZL’s partner site BREATH und senior physician at the Department for Paediatric Pneumology at Hannover Medical School, received this year’s Johannes Wenner research prize, which includes prize money of 15.000 €. The prize is awarded annually by the German Lung Foundation (Deutsche Lungenstiftung) together with the Society of Paediatric Pneumology (Gesellschaft für Pädiatrische Pneumologie) for exceptional research in the area of health service and treatment of children with lung diseases.
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März 17, 2016
Interesting facts, on-site training and plenty of time for chats were again the center of the 3rd seminar for patients with bronchiectasis
On Saturday, March 12th, the third patient seminar for patients with bronchiectasis took place at MHH. Despite of some last minute cancellations, Dr. Felix Ringshausen, senior physician in the pneumology department and expert in the area of bronchiectasis, was able to welcome approx. 60 patients and their relatives.
February 20, 2016
The Fraunhofer-Seminar “Models of Lung Disease 2016”, which took place on January 21st and 22nd at the Clinical Research Center Hannover, once again provided an excellent forum for interaction between academia and industry. Scientists from academic institutions and representatives from the pharmaceutical industry had lively discussions about topics of translational research.
February 15, 20165th Annual Meeting of the German Center for Lung Research (DZL) in Hannover – a great success
February 05, 2016
BREATH supports events for physicians and scientists
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For some time now the BREATH office supports its members in initiating events for physicians and scientists within and beyond the DZL. The support can vary from pure administrative tasks to the handling of finances up to execution of the event, depending on the need of the BREATH faculty member.
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January 13, 2016
BREATH expands its board with a patient representative
On Jan 12 during their general assembly BREATH changed its by-laws and expanded its steering committee with a patient representative. The faculty elected Michael Wilken, who has been a patient and very active patient representative since many years at Hannover Medical School. BREATH is very happy to have been able to find such a qualified candidate for this important role.
November 26, 2015
The HUB has been successfully certified according to DIN EN ISO 9001: 2008
After the Hannover Unified Biobank, the central biobank of BREATH – Member of the German Center for Lung Research (DZL), successfully established a Quality Management System it has been certified according to DIN EN ISO 9001: 2008 by the TÜV NORD in November 2015. This is a remarkable succes since not many biobanks have succeeded in this process so far.
October 07, 2015
ERS Research Award 2015 is awarded to BREATH scientist Antje Prasse
On September 27 the research prize of the European Respiratory Society (ERS) on Idiopathic Lung Fibrosis has been awarded to Professor Dr. Antje Prasse during the annual congress of the ERS in Amsterdam. Professor Prasse has been working at the Hannover site BREATH of the German Center for Lung Research (DZL) since 2014.
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October 5, 2015Where air flows - and where it doesn't
At Hannover Medical School, site BREATH of the German Center for Lung Research, scientists are now able to visualize where air flows in the lungs and where it doesn't, due to a new Magnetic Resonance Tomography (MRT) technique.
For this purpose scientists are using a special MRT spool which is able to detect Fluor (19F). Hannover is the only site in Europe where this technique is available.
September 16, 2015
Radiologists and pneumologists meet for the Expert Forum Lung Fibrosis
On September 9, more than 50 physicians participated in the Expert Forum Lung Fibrosis, for which the Lung Fibrosis Center at Hannover Medical School around Professor Dr. Antje Prasse had invited.
They met to listen to the presentations of the experts at MHH and to the invited keynote speaker, Dr. Wouter von Es, and to discuss cases of radiological data of patients with lung diseases.
July 3, 2015New structure of information evenings at MHH for parents of children with cystic fibrosis
Since last year the physicians at Chrstiane-Herzog Center for Cystic Fibrosis at Hannover Medical School have been offering information evenings for parents of children with cystic fibrosis in a new format. While parents’ evenings have been held since 30 years, the new “workshop structure” is supposed to increase the interaction and empowerment of parents and patients.
June 19, 2015
First BREATH Summer School greeted with enthusiasm by participants and speakers
With the topic „The failing lung – environmental damage and clinical repair”, the first BREATH Summer School took place from 10-13 June 2015 in the heart of the Harz nature reserve and the 21 participants were offered a varied program covering scientific topics, soft skill courses and teamwork, presentations and discussions about careers in and outside the university as well as an outdoor teambuilding event and barbecue night.
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May 25, 2015
New drug for allergic asthma successfully tested
The group around DZL scientist Prof. Dr. Harald Renz, Director of the Institute for Laboratory Medicine at Philipps-Universität Marburg, DZL-site UGMLC, has developed a new agent against allergic asthma. It has recently been tested successfully by order of Sterna Biologicals GmbH & Co. KG under the leadership of Prof. Dr. Norbert Krug, Medical Director at Fraunhofer-ITEM, DZL-site BREATH.
For further information please click here
or contact: norbert.krug@item.fraunhofer.com
Publication:
Krug N, Hohlfeld JM, Kirsten AM, Kornmann O, Beeh KM, Kappeler D, Korn S, Ignatenko S, Timmer W, Rogon C, Zeitvogel J, Zhang N, Bille J, Homburg U, Turowska A, Bachert C, Werfel T, Buhl R, Renz J, Garn H, Renz H. Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme. N Engl J Med. 2015 May 21; 372(21):1987-95.
April 2, 2015
BREATH Scientists decorated at DGP
During this year’s annual meeting of the German Respiratory Society (DGP), which took place in Berlin in early March, three prizes have been awarded to scientists from Hannover Medical School (MHH). All of them are involved in lung research in the context of BREATH, the Hannover site of the German Center for Lung Research.
March 17, 2015
Second round for seminar for patients with “non-CF bronchiectasis“
In the beginning of March the second seminar for patients with non-CF bronchiectasis took place at Hannover Medical School. After its successful launch last year the patients had desired a continuation of this series of seminars and the organizers were very happy to satisfy the requirement.
February 26, 2015
World´s first monograph on mutant-specific therapies
In the beginning of this year the monograph “Mutation-specific therapies in cystic fibrosis – Current status and prospects” by Burkhard Tümmler has been published. Burkhard Tümmler is a scientist at the Hannover site BREATH of the German Center for Lung Research (DZL). This book has been written in collaboration with other scientist also luminaries in the same field like Markus Mall for e.g. who is also scientist and director of the German Center for Lung Research at site Heidelberg.
February 10, 2015
14th Fraunhofer seminar "Models of Lung Disease" - summery
In early February 2015, experts from academia and industry got together already for the 14th time to discuss the current possibilities of experimental lung research and different experimental approaches. About 130 participants attended this two-day event, most of them from European countries, but a few also from Australia and the US. Compared with the previous events of this workshop series, this year’s seminar came up with some novelties – first of all a new name, which changed from “Models of Asthma and COPD” to “Models of Lung Disease”.
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January 19, 2015
AstraZeneca Pneumology Award goes to DZL scientist
On December 12, 2014 AstraZeneca for the first time awarded its Pneumology Award which includes prize money of 20,000 Euro. Its first laureate is Prof. Dr. Sabina Janciauskiene. The scientist from Sweden is doing her research at Hannover Medical School since 2009. She is also member of the research network BREATH, the Hannover site of the German Center for Lung Research (DZL).
Prof. Janciauskiene received the award for her discovery of anti-inflammatory characteristics of alpha1-antitrypsin which open up new therapeutic prospects for inflammatory diseases.
December 4, 2014
Great success for BREATH biobank
At the 3rd National Biobank Symposium, taking place in Berlin, the Hannover Unified Biobank (HUB), biobank of the Hannover Medical School and the DZL site BREATH, has been awarded three prizes for the best scientific posters.
The team of Prof. Dr. Thomas Illig, scientific head of HUB, consisting of Dr. Norman Klopp, Inga Bernemann and Dr. Markus Kersting, presented their work in the areas of infrastructure, quality management and IT-systems and proved the HUB to be an innovative and state-of-the-art biobank.
November 22, 2014
“So, what exactly is Pneumology?“:
Clinicians and researchers from BREATH, the Hannover section of the German Center for Lung Research, and the Department of Respiratory Medicine, took this question as their motto for the 2014 Open Day at Hannover Medical School, which welcomed over 2,000 members of the public on 22 November 2014.
November 4, 2014
"When the lung is shrinking" -
1st patients' seminar for patients with pulmonary fibrosis on the occasion of the launch of the pulmonary fibrosis center at MHH
September 26, 2014
„Life-time achievement in pulmonary hypertension award“ of the European Respiratory Society for Professor Marius Hoeper
At this year's congress of the European Respiratory Society (ERS), which took place from September 6 - 9 in Munich, Professor Dr. Marius Hoeper, Leading Senior Physician at the Department of Respiratory Medicine at Hannover Medical School (MHH) and principal investigator at BREATH, Member of the German Center for Lung Research, has been honored for his lifetime achievements in the field of the research and treatment of pulmonary hypertension (PH).
September 3, 2014
New Metrics for Translational Research: DZL Correspondence in Lancet Respiratory Medicine
The German Center for Lung Research has recently published a letter in Lancet Respiratory Medicine which features the key performance indicators the DZL will use to measure its success in translational research.
The full text may be accessed on the Lancet Respiratory Medicine Website.
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August 22, 2014
12th Annual Molecular Biology and Medicine of the Lung (MBML) Retreat
The prestigious meeting was held in the beautiful historic castle of Rauischholzhausen in Hessen, Germany, from August 4th-6th 2014. The conference featured two Nobel Prize Laureates: Prof. Dr. Robert Huber from the Max Planck Institute for Biochemistry Munich and Nobel Laureate Prof. Dr. Harald Zur Hausen from the German Cancer Research Center Heidelberg.
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August 20, 2014
Novelty at MHH: genetically corrected cells are directly implanted into the lungs
New treatment for rare lung disease in sight
An interdisciplinary research team at Hannover Medical School (MHH) has developed a new therapeutic approach for the treatment of the pulmonary alveolar proteinosis (PAP). The study has now been published in the prestigious journal Science Translational Medicine.
For further information please contact: happle.christine@mh-hannover.de
Publication:
C. Happle et al; Pulmonary transplantation of macrophage progenitors as effective and long-lasting therapy for hereditary pulmonary alveolar proteinosis; Sci Transl Med, 20 August 2014, Vol. 6, Issue 250, p. 250ra113
August 1, 2014
Outpatient non-invasive ventilation reduces the risk of mortality in patients with severe hypercapnic COPD by 76%
A clinical trial* of the group led by PD Dr. Thomas Köhnlein, long-standing pneumologist at the Hannover Medical School and since May 2014 chief physician at the Hospital of St. George in Leipzig, about the non-invasive ventilation of patients with severe COPD has made it into the prestigious journal The Lancet Respiratory Medicine.
For further information please contact: koehnlein.thomas@mh-hannover.de
Publication:
*Köhnlein T et al; Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial. Lancet Respir Med. 2014 Jul, Article in Press
July 10, 2014
ERS Grant 2014 for
Dr. Felix C. Ringshausen
Dr. Felix Ringshausen is senior physician and head of the Christiane Herzog Center for Cystic Fibrosis at the Department of Respiratory Medicine at the MHH. Since 2013 he has been Principal Investigator at DZL with a focus on cystic fibrosis (CF) and non-CF bronchiectasis. Dr. Ringshausen has recently been elected Group Secretary of the Respiratory Infections Group by ERS. At the upcoming ERS conference in Munich he will be awarded the ERS Grant 2014 for the best abstract in the field of „non-CF bronchiectasis“.
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July 4, 2014
Sustainable Effect
The aim of this research team is to display lungs in 3D.
A grant has provided the project with the incentive.
June 18, 2014
On June 17, Professor Dr. Dr. Axel Haverich received the renowned Fritz Behrens Prize for his life's work. The award includes prize money of 30,000 euros and is conferred by the Fritz Behrens Foundation in science every two years. The laudatio was held by Professor Dr. Werner Seeger, CEO and chairman of the board of the German Center for Lung Research (DZL).
June 6, 2014
DZL PI honored with "Röntgenring"
PD Dr. Jens Vogel-Claussen, Prinicpal Investigator at BREATH, partner site of the German Center for Lung Research, is this year's winner of the "Röntgenring". With this award the German Radiology Society honors radiologists who have gained outstanding reputation on a national and international level through excellent scientific work and presentations.
May 28, 2014 Lung experts from around the world meet in Hannover
They traveled from Belgium, France, Israel, Canada, the Netherlands, Switzerland, Spain, the U.S., the UK and Germany to Hannover: About 50 international and a futher 300 German scientists met from 8th to 10th of May at the Palace of the Royal Gardens of Herrenhausen to discuss the latest research and therapeutic approaches for lung diseases.
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May 7, 2014
New research MRI at the CRC Hannover, exclusively for early clinical trials
Publication: American Journal of Respiratory and Critical Care Medicine 2014 Mar 15; 189(6):650-7.
Contact:
Prof. Dr. med. Frank Wacker
Director of the Institute for Diagnostic and Interventional Radiology of Hannover Medical School
Tel.: +49 (0) 511 / 532 - 3422
e-mail: wacker.frank@mh-hannover.de
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April 10, 2014
This year´s DGP awards go to young scientists from the DZL.
To encourage young scientists the German Respiratory Society (DGP) awards prizes each year to young scientists for basic research and clinical research in the field of lung diseases.
März 25, 2014"My visit at the DZL" - Report by Clara Philippi (visitor at MHH)
"In order to get information for my Facharbeit "Comparison of lung function measurements spirometry and body plethysmography," I contacted Dr. Annegret Zurawski, Managing Director of the German Centre for Lung Research (DZL) at Hanover, BREATH. Immediately I received an invitation to visit the DZL at the Hannover Medical School that I had not expected. The more I was delighted when I was able to spend a day at MHH on February 17..."
March 21, 2014
Successful launch of
patient seminar series
"Non-CF bronchiectasis"
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March 10, 2014
"The power of the genes" - BREATH scientists reach top positions in publication analysis
March 6, 2014
LAM – a highly rare disease gets attention
On March 6, the regional group of Hannover LAM Selbsthilfe e.V. Deutschland (LAM = Lymphangioleiomyomatosis) met for the first time with Professor Dr. Tobias Welte, Director of the Department of Respiratory Medicine at Hannover Medical School. Seven women affected by this very rare lung disease as well as a relative had sent a series of questions to Professor Welte to prepare for the meeting with a request for answers. Professor Welte worked through the questionnaire from start to finish with pronounced patience, clarity and empathy.
February 18, 2014
Workshop Summary: 13th Workshop" Models of Asthma and COPD" at the Fraunhofer ITEM, Hannover / Germany, January 24 - 25, 2014
January 23, 2014
BREATH launches a new lecture series for PhD students
„Pneumology for Lung Researchers“
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December 1, 2013
Successful research within the German Center for Lung Research (DZL):
Newly discovered anti-inflammatory characteristics of alpha1-antitrypsin open up therapeutic prospects for inflammatory diseases.
November 2, 2013
18th Hannover Vaccination Symposium
On November 2nd the Hannover Vaccination Symposium was held at Hannover Medical School.
The Center of Competence for Infectious Diseases, made up of six clinics at the MHH, has been holding this symposium for 18 consecutive years as an advanced training course for registered doctors and pediatricians, to give them an overview of the newest developments in the field of vaccination.
October 25, 2013
Lung diseases don´t stop at the border
Besides individual factors, they are often caused by environmental influences or infectious agents. Particularly the threat of infections with an epidemiological potential is increasing – and their control therefore calls for transnational efforts and better coordination of existing national networks.
The German Center for Lung Disease (DZL) strives for an increased European networking, with the competence network CAPNETZ setting a good example.
Oktober 14, 2013
For the first time CAPNETZ Stiftung is awarding a price for exceptional research in the area of community-acquired pneumonia and other infections of the lower respiratory tract.
Application deadline is December 13, 2013
September 19, 2013
French cuisine while discussing the organ lung - CPC Munich invites young DZL scientists to Tours, France
For the first time, CPC Munich, site of the German Center for Lung Research (DZL), invited five young scientist from each DZL site to join the CPC-INSERM Summer Retreat. The retreat is part of the CPC Research School “Lung Biology and Disease” and was held from September 16 – 19, 2013 in Tours, France.
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September 2, 2013
The Lung Information Service (LID) reports:
Nanoparticles functioning as carrier substances for future inhalable influenza vaccinations have the ability to increase the effect of the vaccination. This finding has been made by a group of scientists at the German Center for Lung Research (DZL) under the leadership of professor Armin Braun from Fraunhofer Institute for Toxikology and Experimental Medicine, partner of the DZL site BREATH. The findings have recently been published in the highly respected scientific journal PLOS ONE. The research was conducted by Vanessa Neuhaus, currently working on her PhD at Fraunhofer ITEM.
August 28, 2013
Discussions, open feedback and inspiration at the first BREATH Retreat
On August 21st, 2013 the first full-day retreat of the research network BREATH, site of the German Center for Lung Research (DZL), took place in Hannover. The event was hosted in the Medical Park Hannover, just a few minutes walk from the Hannover Medical School and the Fraunhofer ITEM. The ambience and communicative atmosphere of the venue contributed to the success of the event.
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August 25, 2013
BREATH researcher receives scholarship from the TUI Foundation
Young scientist Dr. Mark Kühnel receives a postdoctoral fellowship of 24.000 Euro from the TUI Foundation for his habilitation. His research focuses on the pathogenic mechanisms that are involved in the development of fibrosis in idiopathic interstitial pneumonia (IIP).
August 10, 2013
Hands-on advice for stereologic analyses in the area of lung research
Professor Matthias Ochs and Professor Dr. Christian Mühlfeld from the Institute of Functional and Applied Anatomy, Hannover Medical School, and principal investigators of the German Center for Lung Research have recently published two review articles in the field of stereology on "Quantitative Microscopy of the lung" in the American Journal of Physiology.
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July 1, 2013
Young Investigator Award of the German Radiological Society goes to a young MHH scientist working at the German Center for Lung Research.
Since 2009 young researchers are honored by the German Radiological Society for their outstanding work and contributions to the congress with the "Young Investigator Award".
At this year´s 94th German Radiology Congress, the award has been presented to Dr. med. Julius Renne, a young researcher at the Institute of Diagnostic and Interventional Radiology of the MHH.
May 4, 2013
The Mukoviszidose e. V. confers Adolf Windorfer Award 2013 to PD Dr. Frauke Stanke
The Mukoviszidose e. V. confers the Adolf Windorfer Award every two years for outstanding work in the field of research and treatment of cystic fibrosis. PD Dr. Frauke Stanke received the award for her work in cooperation with the European cyctic fibrosis twin sibling study
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April 8, 2013
First transition outpatient clinic at the MHH: Christiane Herzog Center for cystic fibrosis sufferers opens its doors
March 1, 2013
Prof. Tobias Welte in an interview with the Lung Information Service on
"Lung Damage from Pneumonia“
Februar 28, 2013
High distinction for MHH research team
Eva Luise Köhler Research Prize awarded to four MHH researchers for novel gene therapy / 50,000 Euros for new therapies in children with rare lung diseases
December 1, 2012
CAPNETZ FOUNDATION becomes partner of the German Center for Lung Research
From January 2013, the competence network CAPNETZ becomes an associate partner of the German Center for Lung Research (DZL). CAPNETZ conducts one of the largest comprehensive epidemiological studies in Europe involving more than 10,000 patients with community-acquired pneumonia. In CAPNETZ, the DZL gains a strong partner
November 27, 2012
The German Chancellor Angela Merkel, at the invitation of the Lower Saxony Prime Minister David McAllister, visited Hannover Medical School to learn about the success of the Excellence Initiative.
On a tour through the relevant research institutes, she looked at the work of two Clusters of Excellence based at the MHH - "REBIRTH" and "Hearing4all"
Oktober 10, 2012
Donor lungs: MHH develops new transport system
Study on the Organ Care System for the lung is successful / publication in the Lancet
An already innovative product developed further: Prof. Dr. Axel Haverich, Head of the Department of Cardiothoracic, Transplantation and Vascular Surgery (HTTG) and his team now use for the lung a method originally designed by the Transmedics company for the heart
September 12, 2012
German premiere: surgeons at Hannover Medical School have performed the first living lung donor transplantation
For the first time in Germany: parents donate parts of their lungs to their child – operation at the MHH is a success / living donors needed due to lack of donor organs